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Rheumatic diseases in pregnancy

Identifieur interne : 002B42 ( Main/Exploration ); précédent : 002B41; suivant : 002B43

Rheumatic diseases in pregnancy

Auteurs : Caroline Gordon [Royaume-Uni]

Source :

RBID : ISTEX:C8CD5B414D6F7F50DB7EC2606988E0CFDE067B8B

English descriptors

Abstract

Rheumatic diseases often present in women of childbearing age. Fortunately, most forms of inflammatory arthritis improve in pregnancy and maternal or fetal complications are rare. Drug therapy may need to be modified as most drugs cross the placenta but only a few are definitely teratogenic. Ankylosing spondylitis may not remit in pregnancy and can be difficult to manage as the high dose non-steroidal anti-inflammatory drugs usually taken by the patient must be discontinued. Providing that systemic lupus erythematosus is well-controlled at the onset of pregnancy, the prognosis for mother and baby is good. Neonatal lupus syndrome is uncommon. The outcome in the rarer systemic conditions such as scleroderma and vasculitis is less predictable and the risk of serious deterioration in the mother is greater. Close liaison between obstetricians and rheumatologists will ensure optimal management of these potentially complicated pregnancies.

Url:
DOI: 10.1016/S0957-5847(09)80009-7


Affiliations:


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Le document en format XML

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<term>Active disease</term>
<term>Active lupus</term>
<term>Ankylosing spondylitis</term>
<term>Anticardiolipin antibodies</term>
<term>Antiphospholipid</term>
<term>Antiphospholipid antibodies</term>
<term>Antiphospholipid antibody syndrome</term>
<term>Antiphospholipid syndrome</term>
<term>Arthritis</term>
<term>Arthritis rheum</term>
<term>Aspirin</term>
<term>Cardiac failure</term>
<term>Clinical rheumatology</term>
<term>Congenital heartblock</term>
<term>Connective tissue</term>
<term>Considerable risk</term>
<term>Contraceptive pill</term>
<term>Current obstetrics</term>
<term>Debatable issue</term>
<term>Disease activity</term>
<term>Disease flare</term>
<term>Dose aspirin</term>
<term>Drug treatment</term>
<term>Early pregnancy</term>
<term>Epidural anaesthesia</term>
<term>Erythematosus</term>
<term>Fetal</term>
<term>Fetal complications</term>
<term>Fetal development</term>
<term>Fetal loss</term>
<term>Fetal outcome</term>
<term>Fetus</term>
<term>First time</term>
<term>Haemolytic anaemia</term>
<term>Hellp syndrome</term>
<term>Hepatic infarction</term>
<term>High levels</term>
<term>High risk</term>
<term>Hypertension</term>
<term>Inflammatory</term>
<term>Inflammatory arthritis</term>
<term>Inflammatory arthropathies</term>
<term>Inflammatory processes</term>
<term>Interuterine growth retardation</term>
<term>Lupus</term>
<term>Lupus anticoagulant</term>
<term>Lupus erythematosus</term>
<term>Lupus flare</term>
<term>Maternal complications</term>
<term>Maternal disease</term>
<term>Neonatal lupus</term>
<term>Neonatal lupus syndrome</term>
<term>Obstet gynecol</term>
<term>Oxford textbook</term>
<term>Oxford university press</term>
<term>Photosensitive rashes</term>
<term>Polyarteritis nodosa</term>
<term>Postpartum flare</term>
<term>Prednisolone</term>
<term>Pregnancy</term>
<term>Pregnant mother</term>
<term>Pregnant patient</term>
<term>Preterm delivery</term>
<term>Pulmonary hypertension</term>
<term>Recurrent miscarriages</term>
<term>Renal</term>
<term>Renal disease</term>
<term>Renal involvement</term>
<term>Rheum</term>
<term>Rheumatic</term>
<term>Rheumatic disease</term>
<term>Rheumatic diseases</term>
<term>Rheumatoid arthritis</term>
<term>Rheumatology</term>
<term>Skin rashes</term>
<term>Spondylitis</term>
<term>Spontaneous abortion</term>
<term>Steroid</term>
<term>Steroid therapy</term>
<term>Syndrome</term>
<term>Systemic</term>
<term>Systemic disease</term>
<term>Systemic lupus erythematosus</term>
<term>Systemic sclerosis</term>
<term>Third trimester</term>
<term>Vasculitis</term>
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<div type="abstract" xml:lang="en">Rheumatic diseases often present in women of childbearing age. Fortunately, most forms of inflammatory arthritis improve in pregnancy and maternal or fetal complications are rare. Drug therapy may need to be modified as most drugs cross the placenta but only a few are definitely teratogenic. Ankylosing spondylitis may not remit in pregnancy and can be difficult to manage as the high dose non-steroidal anti-inflammatory drugs usually taken by the patient must be discontinued. Providing that systemic lupus erythematosus is well-controlled at the onset of pregnancy, the prognosis for mother and baby is good. Neonatal lupus syndrome is uncommon. The outcome in the rarer systemic conditions such as scleroderma and vasculitis is less predictable and the risk of serious deterioration in the mother is greater. Close liaison between obstetricians and rheumatologists will ensure optimal management of these potentially complicated pregnancies.</div>
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